Aug 31, 2013, 9:23 AM EST
The former Sevilla striker was found in the box by a pinpoint cross from Pablo Zabaleta and he could hardly miss as Negredo headed downwards past a helpless Alan McGregor.
It was the second week in a row that Negredo had jumped off the bench to score for City and he must now be pushing for his first start for Manuel Pellegrini’s side.
The opening goal was slightly harsh on Hull who acquitted themselves well for the first 60 minutes but came undone just after the hour.
Can Man City seal all three points?
Watch the final minutes live via NBC Sports Live Extra.
- Looking back on 2013: Talking through Real Salt Lake’s path to MLS Cup 1
- WATCH: PST Extra – Will Everton upset Arsenal? Can Man United bounce back vs. Newcastle? 0
- Prindi’s Premier League Picks: Sunderland and Everton to upset odds 4
- Kyle Martino chats Andre Villas-Boas drama and Premier League parity 0
- Mike Magee Wins 2013 MLS Most Valuable Player Award 6
- USA fear toughest ever World Cup draw but relish chance to make history 6
- 2014 FIFA World Cup Draw: Everything you need to know 4
- Premier League Playback: Moyes needs more, Suarez is Superman, Altidore (finally) off the mark 9
- What US Soccer wants from the World Cup draw (22)
- Sit down with Orlando City SC: Taking on Beckham, emulating the Timbers and Kaka in 2015 – Part I (21)
- Video of Jermaine Jones’ terrific goal Saturday for Schalke (20)
- 2014 FIFA World Cup Draw: The sum of all fears scenario for the United States (17)
- World Cup Draw: United States in Pot Three (11)