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Watch Live: Manchester United vs. Southampton (lineups and discuss)

Oct 19, 2013, 9:14 AM EST

Robin Van Persie, Phil Jones AP

Manchester United are hoping they don’t suffer successive home defeats for the first time since 2002 when high flying Southampton roll into Old Trafford.

Watch live at 10am ET,  on NBCSN and online via NBC Sports Live Extra

The Saints are currently fourth in the table, four points ahead of the Red Devils heading into this one. Can Mauricio Pochettino‘s men pull of a huge upset against David Moyes‘ United side?

United have struggled in their seven PL games so far, with three defeats leaving plenty of questions asked about Sir Alex Ferguson‘s successor. Wayne Rooney and Robin van Persie start up front together today, with Adnan Januzaj keeping his place in the lineup after his two-goal heroics against Sunderland last-time out.

More defensive changes for Moyes, as Phil Jones and Johnny Evans play in central defense, with Nemanja Vidic and Rio Ferdinand both out.

For Saints, they leave out England international Rickie Lambert and bring in Jay Rodriguez, while Luke Shaw replaces Danny Fox at left back.

LINEUPS

Manchester United: De Gea; Rafael, Jones, Evans, Evra; Nani, Carrick, Fellaini, Januzaj; Rooney, van Persie. Subs: Lindegaard, Giggs, Smalling, Hernandez, Welbeck, Kagawa, Zaha.

Southampton: Boruc, Clyne, Fonte, Lovren, Shaw, Wanyama, Schneiderlin, S. Davis, Lallana (c), Rodriguez, Osvaldo. Subs: K. Davis (GK), Lambert, Ward-Prowse, Cork, Guly, Chambers, Hooiveld.

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